(R)-Viloxazine Hydrochloride(CAS: 56287-63-9)

(R)-Viloxazine Hydrochloride is a crystalline compound with a molecular weight of approximately 291.7 g/mol. It has a solubility of about 29 mg/mL in water. It is relatively stable under normal conditions but can react with bases to form the free base. The compound is commonly used in pharmaceutical applications and has a bitter taste.

(R)-Viloxazine Hydrochloride is typically synthesized through a series of steps including the condensation of a suitable aromatic amine with a chloroacetyl chloride, followed by hydrogenation to introduce the (R)-configuration. The reaction is catalyzed by palladium and uses a ligand to control the enantiomeric selectivity, achieving a yield of around 80%.

(R)-Viloxazine Hydrochloride is primarily used in the pharmaceutical industry. It is an intermediate used in the synthesis of certain antidepressant drugs. In addition, it may have applications in the polymer and sensor industries due to its chemical properties.

When handling (R)-Viloxazine Hydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up using appropriate methods and equipment, and a safety data sheet (SDS) should be consulted for detailed procedures.