Compound Q&A

How is (R)-Viloxazine Hydrochloride (CAS: 56287-63-9) typically synthesized?

Answer

(R)-Viloxazine Hydrochloride
(R)-Viloxazine Hydrochloride is typically synthesized through a series of steps including the condensation of a suitable aromatic amine with a chloroacetyl chloride, followed by hydrogenation to introduce the (R)-configuration. The reaction is catalyzed by palladium and uses a ligand to control the enantiomeric selectivity, achieving a yield of around 80%.

About

CAS No 56287-63-9
English Name (R)-Viloxazine Hydrochloride
Molecular Formula C13H20ClNO3
Molecular Weight 273.76 g/mol
SMILES CCOC1=CC=CC=C1OCC2CNCCO2.Cl
InChIKey HJOCKFVCMLCPTP-RFVHGSKJSA-N
Last Updated: 2025-12-31 16:27

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