(3R)-4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-morpholinecarboxylic acid(CAS: 869681-70-9)

This compound is a white crystalline solid with a molecular weight of approximately 264.36 g/mol. It has a pKa of around 11.3, indicating basic properties. The compound is poorly soluble in water but soluble in organic solvents such as methanol and dimethylformamide. It is reactive towards nucleophiles and can undergo esterification and amide formation reactions.

This compound can be synthesized via a multi-step process starting with morpholine and 2-methyl-2-propanol. The key steps involve esterification followed by protection and deprotection of functional groups. Commonly used reagents include acyl chlorides or mixed anhydrides, with HBTU or EDC as coupling agents. The overall yield is moderate to good, depending on the purity of the intermediates.

This compound is primarily used in the pharmaceutical industry for the synthesis of bioactive molecules. It also finds applications in polymer chemistry, where it can be used as a monomer or additive. Additionally, it is utilized in the formulation of certain sensors and as a precursor in semiconductor manufacturing.

Proper handling procedures include the use of gloves, safety goggles, and a lab coat. Store the compound in a cool, dry place away from direct sunlight and heat sources. Work should be conducted in a fume hood to minimize exposure to volatile components. In case of spill, neutralize with an appropriate acid-base buffer and dispose of according to local waste regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.