Compound Q&A

How is (3R)-4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-morpholinecarboxylic acid (CAS: 869681-70-9) typically synthesized?

Answer

(3R)-4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-morpholinecarboxylic acid
This compound can be synthesized via a multi-step process starting with morpholine and 2-methyl-2-propanol. The key steps involve esterification followed by protection and deprotection of functional groups. Commonly used reagents include acyl chlorides or mixed anhydrides, with HBTU or EDC as coupling agents. The overall yield is moderate to good, depending on the purity of the intermediates.

About

English Name (3R)-4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-morpholinecarboxylic acid
Molecular Formula C10H17NO5
Molecular Weight 231.24799999999996 g/mol
SMILES CC(C)(C)OC(=O)N1CCOC[C@@H]1C(=O)O
InChIKey KVXXEKIGMOEPSA-SSDOTTSWSA-N
Last Updated: 2025-10-07 19:42

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