Compound Q&A
How is (3R)-4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-morpholinecarboxylic acid (CAS: 869681-70-9) typically synthesized?
Answer
![(3R)-4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-morpholinecarboxylic acid](https://static.chemtradehub.com/structs/869/869681-70-9-39cb.webp "(3R)-4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-morpholinecarboxylic acid")
This compound can be synthesized via a multi-step process starting with morpholine and 2-methyl-2-propanol. The key steps involve esterification followed by protection and deprotection of functional groups. Commonly used reagents include acyl chlorides or mixed anhydrides, with HBTU or EDC as coupling agents. The overall yield is moderate to good, depending on the purity of the intermediates.
About
CAS No
869681-70-9
English Name
(3R)-4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-morpholinecarboxylic acid
Molecular Formula
C10H17NO5
Molecular Weight
231.25 g/mol
SMILES
CC(C)(C)OC(=O)N1CCOC[C@@H]1C(=O)O
InChIKey
KVXXEKIGMOEPSA-SSDOTTSWSA-N
Last Updated: 2025-10-07 19:42
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