(2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid(CAS: 781658-23-9)

The compound (2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid has a crystalline form with a molecular weight of approximately 170.24 g/mol. It is sparingly soluble in water and more soluble in organic solvents. Chemically, it is moderately reactive, particularly with bases and nucleophiles. It is stable under normal conditions but may degrade upon prolonged exposure to acidic or basic environments.

This compound can be synthesized via a multi-step process involving the condensation of amino acids and subsequent derivatization. Commonly, it is prepared from (2S,3R)-3-methyl-4-oxopentanoic acid via amino group addition. The reaction typically requires catalysts like Lewis acids and has good selectivity, with yields ranging from 70% to 90% depending on the method.

This compound is primarily used in the pharmaceutical industry for its potential in drug development, particularly in the synthesis of biologically active molecules. It also finds applications in the chemical and polymer industries for producing specialized materials and in the semiconductor industry for certain chemical processes.

When handling (2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid, it is essential to use appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. Store it in a cool, dry place away from direct sunlight and flammable materials. In case of spill, use appropriate absorbents and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.