Compound Q&A
How is (2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid (CAS: 781658-23-9) typically synthesized?
Answer
This compound can be synthesized via a multi-step process involving the condensation of amino acids and subsequent derivatization. Commonly, it is prepared from (2S,3R)-3-methyl-4-oxopentanoic acid via amino group addition. The reaction typically requires catalysts like Lewis acids and has good selectivity, with yields ranging from 70% to 90% depending on the method.
About
CAS No
781658-23-9
English Name
(2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid
Molecular Formula
C6H13NO3
Molecular Weight
147.17 g/mol
SMILES
CC([C@@H]([C@@H](C(=O)O)N)C)O
InChIKey
OSCCDBFHNMXNME-DSDZBIDZSA-N
Last Updated: 2025-09-07 10:19
