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6-Fluoro-4H-chromen-4-one(CAS: 105300-38-7)

6-Fluoro-4H-chromen-4-one
CAS Number

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Basic Information

Molecular Formula
C9H5FO2
Molecular Weight
164.14 g/mol

Physical Properties

Melting Point
166.0 to 170.0 deg-C
Boiling Point
249.7±40.0 ºC (760 Torr),
Flash Point
101.8±22.2 ºC,

Chemical Identifiers

SMILES
C1=CC2=C(C=C1F)C(=O)C=CO2
InChIKey
WHIGSYZUTMYUAX-UHFFFAOYSA-N

Database References

MDL Number
MFCD03094002

FAQ

6-Fluoro-4H-chromen-4-one (CAS: 105300-38-7) falls under the scope of the REACH regulation in the European Union, and may require registration for use. It is also subject to the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) which mandates specific hazard communication and labeling. In the USA, the Environmental Protection Agency (EPA) and FDA may have additional regulatory requirements. Safe handling, storage, and disposal practices must be followed in accordance with local, state, and federal regulations.
In synthesis, 6-Fluoro-4H-chromen-4-one (CAS: 105300-38-7) can be replaced by structurally similar chromone derivatives such as 4-fluoro-6-methyl-4H-chromen-4-one or 6-bromo-4H-chromen-4-one. Other alternatives include using different aromatic nuclei or substituents to achieve similar properties. Synthesis can be optimized using alternative reagents like palladium catalysts, which provide more environmentally friendly and efficient pathways.
The market and research trends for 6-Fluoro-4H-chromen-4-one (CAS: 105300-38-7) indicate growing interest in its applications as a precursor for pharmaceuticals and dyes. Recent studies focus on its use in drug design and development, particularly in the synthesis of anti-inflammatory and anti-cancer agents. Market trends suggest increasing demand for this compound due to its unique biological activities and potential in various research fields. However, the market is also influenced by supply chain issues and environmental regulations.
Waste containing 6-Fluoro-4H-chromen-4-one (CAS: 105300-38-7) should be collected in appropriate containers and stored under controlled conditions to prevent degradation and contamination. For disposal, professional waste treatment facilities should be used to ensure safe incineration or chemical neutralization. Environmental protection measures, such as proper sealing and labeling, are essential to avoid release into the environment. Compliance with local and federal regulations is mandatory to ensure safe waste handling and disposal.

Safety Notice

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