(2-Fluoro-6-isopropoxyphenyl)boronic acid(CAS: 870777-17-6)

(2-Fluoro-6-isopropoxyphenyl)boronic acid (CAS: 870777-17-6) is a white crystalline solid with a molecular weight of approximately 300.29 g/mol. It has a low solubility in water but is soluble in organic solvents like dichloromethane and acetonitrile. This compound exhibits moderate reactivity in Suzuki coupling reactions, making it useful in organic synthesis. It is stable under normal conditions but should be stored away from heat and moisture.

(2-Fluoro-6-isopropoxyphenyl)boronic acid (CAS: 870777-17-6) can be synthesized via a boronate ester formation from 2-fluoro-6-isopropoxyphenol and sodium borohydride. The reaction is typically carried out in the presence of a base such as potassium carbonate in an aprotic solvent like dimethylformamide (DMF). The yield is usually around 75-85%, with good selectivity for the boronic acid product.

(2-Fluoro-6-isopropoxyphenyl)boronic acid (CAS: 870777-17-6) is used in the pharmaceutical industry for the synthesis of drug intermediates and in the polymer industry for the preparation of functional polymers. It also finds applications in the development of sensors and as a building block in the synthesis of semiconducting materials. Its utility in organic synthesis makes it a valuable reagent in academic and industrial settings.

When handling (2-Fluoro-6-isopropoxyphenyl)boronic acid (CAS: 870777-17-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The material should be used in a well-ventilated fume hood to prevent inhalation. Spills should be handled with care, using appropriate cleaning agents and disposing of waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal guidelines.