Compound Q&A
How is (2-Fluoro-6-isopropoxyphenyl)boronic acid (CAS: 870777-17-6) typically synthesized?
Answer
(2-Fluoro-6-isopropoxyphenyl)boronic acid (CAS: 870777-17-6) can be synthesized via a boronate ester formation from 2-fluoro-6-isopropoxyphenol and sodium borohydride. The reaction is typically carried out in the presence of a base such as potassium carbonate in an aprotic solvent like dimethylformamide (DMF). The yield is usually around 75-85%, with good selectivity for the boronic acid product.
About
CAS No
870777-17-6
English Name
(2-Fluoro-6-isopropoxyphenyl)boronic acid
Molecular Formula
C9H12BFO3
Molecular Weight
198 g/mol
SMILES
CC(OC1=C(B(O)O)C(F)=CC=C1)C
InChIKey
WVAMTUDWTJMGSG-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
