1-(2-Chloro-5-fluorophenyl)ethanone(CAS: 2965-16-4)

1-(2-Chloro-5-fluorophenyl)ethanone (CAS: 2965-16-4) is a white crystalline solid with a molecular weight of approximately 222.59 g/mol. It is slightly soluble in water and more soluble in organic solvents like acetone and chloroform. The compound shows good reactivity towards nucleophiles and electrophiles, making it useful in various synthetic reactions.

1-(2-Chloro-5-fluorophenyl)ethanone (CAS: 2965-16-4) is commonly synthesized via the reaction of 2-chloro-5-fluorophenylacetonitrile with hydroiodic acid, followed by hydrolysis to form the ketone. The reaction is selective and yields up to 95% pure product under optimized conditions.

1-(2-Chloro-5-fluorophenyl)ethanone (CAS: 2965-16-4) is primarily used in the pharmaceutical and chemical industries for the synthesis of intermediates and active pharmaceutical ingredients. It also has potential applications in polymer synthesis and as a sensor material.

When handling 1-(2-Chloro-5-fluorophenyl)ethanone (CAS: 2965-16-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a dry, well-ventilated area, preferably under a fume hood. In case of spill, contain the material with absorbent paper and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.