Actinomycin D(CAS: 50-76-0)

Actinomycin D, CAS 50-76-0, is a cyclic depsipeptide antibiotic with a molecular weight of approximately 925.65 g/mol. It is sparingly soluble in water and ethanol. Actinomycin D exhibits significant reactivity towards nucleic acids, making it a potent antitumor agent. It typically forms a crystalline solid at room temperature.

Actinomycin D (CAS: 50-76-0) is synthesized through semi-synthetic methods, starting from actinorhodin, a natural product from Streptomyces bacteria. The synthesis involves several steps, including acetylation, cyclization, and modification of the molecule's structure to achieve the desired antitumor activity.

Actinomycin D (CAS: 50-76-0) is primarily used in the pharmaceutical industry for its antitumor properties. It is also used in research for its ability to inhibit DNA and RNA synthesis, making it valuable in molecular biology and genetic studies.

When handling Actinomycin D (CAS: 50-76-0), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be handled with caution using appropriate absorbent materials and followed by thorough cleaning and disposal according to safety data sheet (SDS) guidelines.