2-[(4-Methyl-1-piperazinyl)methyl]benzonitrile(CAS: 864069-00-1)

2-[(4-Methyl-1-piperazinyl)methyl]benzonitrile is a colorless to light yellow liquid with a molecular weight of approximately 248.22 g/mol. It has a density of about 1.08 g/cm³ and a boiling point of around 245°C. The compound is slightly soluble in water but miscible with organic solvents. It is moderately reactive, particularly towards nucleophiles, and can undergo various reaction types such as addition and substitution reactions.

2-[(4-Methyl-1-piperazinyl)methyl]benzonitrile is synthesized via a multi-step process involving the reaction of 4-methylpiperazine with benzonitrile followed by alkylation. Commonly, the reaction is performed under basic conditions using sodium hydrogen carbonate as a catalyst. The yield is typically around 75-85%, and the product is isolated by conventional techniques such as column chromatography.

2-[(4-Methyl-1-piperazinyl)methyl]benzonitrile is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring specific functional groups. It is also utilized in the polymer industry for enhancing the properties of certain polymers. Additionally, it finds application in the production of sensors and semiconductors, where its unique chemical properties are advantageous.

Handling 2-[(4-Methyl-1-piperazinyl)methyl]benzonitrile requires appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.