3-Methyl-5-phenyl-1,2-oxazole-4-carbaldehyde(CAS: 89479-66-3)

The physical properties of 3-Methyl-5-phenyl-1,2-oxazole-4-carbaldehyde include a crystalline form with a molecular weight of approximately 222.26 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is a reactive compound known for its ability to form stable complexes with various metal ions and undergo electrophilic aromatic substitution reactions.

3-Methyl-5-phenyl-1,2-oxazole-4-carbaldehyde is typically synthesized through the condensation of 3-methyl-5-phenyl-1,2-oxazole with formaldehyde, often catalyzed by a strong acid like sulfuric acid. The reaction is carried out under reflux conditions to ensure complete conversion and high yield. The method is selective and yields a product with good purity.

3-Methyl-5-phenyl-1,2-oxazole-4-carbaldehyde is used in various industries, particularly in the pharmaceutical sector for the synthesis of drugs, and in the chemical industry for the production of dyes and other organic compounds. Its application in polymer synthesis and as a precursor for semiconductor materials is also notable.

When handling 3-Methyl-5-phenyl-1,2-oxazole-4-carbaldehyde, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or within a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed spill response procedures and emergency contact information.