8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one(CAS: 50892-62-1)

8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one is a white to off-white solid with a molecular weight of approximately 308.67 g/mol. It has a high solubility in organic solvents like DMSO and moderate solubility in water. This compound is relatively stable under normal conditions but can react with strong bases or acids. It is known for its diazepine ring and chlorine substituent, which make it an interesting compound for various applications.

8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one can be synthesized through a multi-step process involving the condensation of benzophenone imine with 1,4-diazepine-1,4-dicarboxylic acid, followed by a series of ring closures and chlorination reactions. This synthesis often requires the use of catalysts and high temperatures, with a typical yield of around 70-80%.

8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one is primarily used in the pharmaceutical industry for the development of new drugs. It also has potential applications in the production of polymers, sensors, and semiconductors due to its unique chemical structure and reactivity.

When handling 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize exposure. In case of a spill, immediately clean it up using appropriate absorbent materials and consult the safety data sheet (SDS) for further guidance on disposal and cleanup procedures.