Compound Q&A

How is 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one (CAS: 50892-62-1) typically synthesized?

Answer

8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one can be synthesized through a multi-step process involving the condensation of benzophenone imine with 1,4-diazepine-1,4-dicarboxylic acid, followed by a series of ring closures and chlorination reactions. This synthesis often requires the use of catalysts and high temperatures, with a typical yield of around 70-80%.

About

CAS No 50892-62-1
English Name 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
Molecular Formula C13H9ClN2O
Molecular Weight 244.681 g/mol
SMILES C1=CC=C2C(=C1)C(=O)NC3=C(N2)C=CC(=C3)Cl
InChIKey YVWNDABPZGGQFE-UHFFFAOYSA-N
Last Updated: 2025-10-10 21:10

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