3-Bromo-6-methoxy-2-methylpyridine(CAS: 126717-59-7)

3-Bromo-6-methoxy-2-methylpyridine is a crystalline solid with a molecular weight of approximately 222.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound is moderately reactive with strong nucleophiles and electrophiles. It decomposes at high temperatures and reacts with strong acids and bases.

3-Bromo-6-methoxy-2-methylpyridine can be synthesized via the bromination of 6-methoxy-2-methylpyridine using N-bromosuccinimide (NBS) as the brominating agent in the presence of a radical initiator like benzoyl peroxide. The reaction is typically performed in an inert atmosphere and the product is purified by recrystallization.

3-Bromo-6-methoxy-2-methylpyridine is used in the pharmaceutical industry for the synthesis of certain intermediates and drugs. It also finds applications in the polymer industry as a precursor for the production of certain plastics and resins. Additionally, it is used in the field of sensors for its reactivity with specific analytes.

When handling 3-Bromo-6-methoxy-2-methylpyridine, appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully using appropriate absorbents, and the area should be thoroughly decontaminated. Refer to the Material Safety Data Sheet (MSDS/SDS) for specific handling and disposal instructions.