4-Benzoylphenyl acrylate(CAS: 22535-49-5)

4-Benzoylphenyl acrylate (CAS: 22535-49-5) is a clear, colorless to slightly yellow liquid at room temperature. It has a molecular weight of approximately 258.24 g/mol and a melting point around -25°C. The compound is poorly soluble in water but soluble in organic solvents like ethanol and acetone. It is reactive towards nucleophiles and can undergo polymerization under certain conditions.

4-Benzoylphenyl acrylate is typically synthesized through the condensation of benzoyl chloride with phenyl acetylene. This process involves heating the reactants in the presence of an organic solvent like toluene, often with a phase transfer catalyst to enhance the reaction rate and yield. The reaction proceeds stereoselectively to form the desired enantiomer with high selectivity, yielding a product with a purity of over 95%.

4-Benzoylphenyl acrylate is used in various industries. It is a key intermediate in the production of polymers and adhesives, where it contributes to the development of high-performance materials with improved mechanical properties. Additionally, it has applications in the pharmaceutical industry for synthesizing certain types of drugs, and it can also be used in the formulation of certain sensors and semiconductors.

When handling 4-Benzoylphenyl acrylate (CAS: 22535-49-5), it is crucial to use personal protective equipment (PPE) including gloves, goggles, and a lab coat to protect against skin and eye contact. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled by neutralizing the acid with a base and then properly disposing of the waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.