Filanesib(CAS: 885060-09-3)

Filanesib is a yellow crystalline solid with a molecular weight of approximately 739.75 g/mol. It has a solubility of about 0.012 mg/mL in water and is poorly soluble in common organic solvents. Chemically, Filanesib is stable under normal conditions but may react with strong acids or bases. It is a potent inhibitor of the p70S6 kinase, making it a critical drug candidate in oncology research.

Filanesib is synthesized through a multi-step process involving condensation reactions, ring formation, and functional group transformations. Commonly, it uses catalysts such as palladium or titanium complexes. The synthesis yields a selective and potent inhibitor with a high purity, ensuring its efficacy in clinical trials and research.

Filanesib is primarily used in the pharmaceutical industry for its potential in oncology. It is also being explored in research for its effects on cellular signaling pathways. While its industrial applications are currently limited, it shows promise in developing new treatments for various cancers and other diseases.

When handling Filanesib, wear appropriate personal protective equipment (PPE) such as gloves and lab coats. Work in a well-ventilated area or under a fume hood to minimize inhalation risks. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, clean up immediately and refer to the Safety Data Sheet (SDS) for specific guidance on disposal guidelines.