5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine(CAS: 15884-86-3)

5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine is a white crystalline solid. Its molecular weight is approximately 188.18 g/mol. It is slightly soluble in water and soluble in organic solvents like ethanol and acetone. The compound is known for its stability and reactivity towards nucleophiles, particularly amines and thiols.

5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine is usually synthesized by the reaction of 5-chloromethoxymethyl-1,3,4-thiadiazol-2-amine with an amine. This process involves the substitution of the chlorine atom with the amino group, catalyzed by a base such as potassium hydroxide. The yield is generally around 85%, and the reaction is carried out in an aprotic solvent like dimethylformamide.

5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine is used in pharmaceuticals for the synthesis of certain drugs, in polymers as a stabilizer, and in sensors for its reactivity towards various analytes. It also has applications in the semiconductor industry for its stability and functional groups.

When handling 5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine, always wear appropriate personal protective equipment (PPE) including gloves and goggles. Work in a well-ventilated area or fume hood. Follow standard safety protocols and keep the compound away from heat and ignition sources. In case of a spill, sweep up the solid material and dispose of it according to the SDS (Safety Data Sheet) guidelines. Always consult the SDS for detailed information.