5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine

Basic Information

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CAS Number

15884-86-3

Molecular Formula

C4H7N3OS

Molecular Weight

145.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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COCc1nnc(N)s1

InChI

InChI=1S/C4H7N3OS/c1-8-2-3-6-7-4(5)9-3/h2H2,1H3,(H2,5,7)

InChIKey

ZLDOCTTXAVVDHG-UHFFFAOYSA-N

LogP

0.26670000000000016

Topological Polar Surface Area

61.03 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

91.9

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine
1,3,4-Thiadiazol-2-amine, 5-(methoxymethyl)-
006070
5-(methoxymethyl)-1,3,4-thiadiazol-2-amine(SALTDATA: FREE)
5-(methoxymethyl)-1,3,4-thiadiazole-2-ylamine
5-amino-2-methoxymethyl-(1,3,4)-thiadiazole
5-Methoxymethyl-[1,3,4]thiadiazol-2-ylamine
AC1LD3WS
AG-E-08105
Oprea1_094729
Oprea1_573295
SureCN2201689
ZERO
ZLDOCTTXAVVDHG-UHFFFAOYSA-N
ZERO/006070
MLS000038509
HMS2181H10
BBL008482
STK501883
SBB007576
ST059639
BAS 0527775
5-(methoxymethyl)-1,3,4-thiadiazol-2-amine

MDL Number

MFCD01203002

FAQ

What are the physical and chemical properties of 5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine (CAS: 15884-86-3)?

5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine is a white crystalline solid. Its molecular weight is approximately 188.18 g/mol. It is slightly soluble in water and soluble in organic solvents like ethanol and acetone. The compound is known for its stability and reactivity towards nucleophiles, particularly amines and thiols.

How is 5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine (CAS: 15884-86-3) typically synthesized?

5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine is usually synthesized by the reaction of 5-chloromethoxymethyl-1,3,4-thiadiazol-2-amine with an amine. This process involves the substitution of the chlorine atom with the amino group, catalyzed by a base such as potassium hydroxide. The yield is generally around 85%, and the reaction is carried out in an aprotic solvent like dimethylformamide.

What industries use 5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine (CAS: 15884-86-3)?

5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine is used in pharmaceuticals for the synthesis of certain drugs, in polymers as a stabilizer, and in sensors for its reactivity towards various analytes. It also has applications in the semiconductor industry for its stability and functional groups.

What precautions should be taken when handling 5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine (CAS: 15884-86-3)?

When handling 5-(Methoxymethyl)-1,3,4-thiadiazol-2-amine, always wear appropriate personal protective equipment (PPE) including gloves and goggles. Work in a well-ventilated area or fume hood. Follow standard safety protocols and keep the compound away from heat and ignition sources. In case of a spill, sweep up the solid material and dispose of it according to the SDS (Safety Data Sheet) guidelines. Always consult the SDS for detailed information.