Methyl 2-amino-5-nitrobenzoate(CAS: 3816-62-4)

CAS Number
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Basic Information
Molecular Formula
C8H8N2O4
Molecular Weight
196.16 g/mol
Physical Properties
Boiling Point
377.9℃ at 760 mmHg
Chemical Identifiers
SMILES
COC(=O)C1=C(C=CC(=C1)[N+](=O)[O-])N
InChIKey
VOQBLPBLKSXCDB-UHFFFAOYSA-N
Database References
MDL Number
MFCD00278157
FAQ
Methyl 2-amino-5-nitrobenzoate (CAS: 3816-62-4) is a solid, crystalline compound. Its molecular weight is approximately 216.14 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound is known for its stability in neutral and slightly acidic solutions. It is not highly reactive under normal conditions but may undergo nitro group reduction under reducing conditions.
Methyl 2-amino-5-nitrobenzoate is typically synthesized via the nitration of methyl 2-aminobenzoate. This process involves reacting methyl 2-aminobenzoate with nitric acid in the presence of a catalyst such as sulfuric acid. The nitration step yields the target compound with good yield and selectivity. The process requires careful control of temperature and reaction time to avoid side reactions.
Methyl 2-amino-5-nitrobenzoate (CAS: 3816-62-4) is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also used in the polymer industry as a stabilizer and in the electronics industry for the production of sensors and semiconductors. Its use in these industries is primarily due to its unique chemical functionality and reactivity.
When handling Methyl 2-amino-5-nitrobenzoate (CAS: 3816-62-4), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up using appropriate absorbent materials. Safety data sheets (SDS) should be consulted for detailed emergency response and handling procedures.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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