3-Fluoro-2-nitropyridine(CAS: 54231-35-5)

3-Fluoro-2-nitropyridine (CAS: 54231-35-5) is a crystalline solid with a molecular weight of approximately 164.04 g/mol. It has low solubility in water but is more soluble in organic solvents like ethanol and chloroform. Chemically, it is highly reactive, particularly towards nucleophiles and reductants, and may undergo substitution and reduction reactions.

3-Fluoro-2-nitropyridine is typically synthesized via the nitration of 2-fluoropyridine. This process involves treating 2-fluoropyridine with a nitration reagent such as fuming sulfuric acid and nitric acid in the presence of a suitable solvent. The reaction is carried out under controlled conditions to achieve high selectivity and yield.

3-Fluoro-2-nitropyridine (CAS: 54231-35-5) is used in various industries, including pharmaceuticals for the synthesis of certain medicinal compounds, and in the production of sensors and semiconductors due to its unique chemical properties.

When handling 3-Fluoro-2-nitropyridine (CAS: 54231-35-5), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be handled with caution, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures.