TOTU(CAS: 136849-72-4)

TOTU (CAS: 136849-72-4) is a white crystalline solid with a molecular weight of approximately 318.19 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and acetonitrile. TOTU is known to be a highly reactive compound, readily forming adducts with nucleophiles and is used in organic synthesis due to its reactivity.

TOTU (CAS: 136849-72-4) is synthesized through the alkylation of an appropriate thioester with an organometallic reagent like lithium diisopropylamide (LDA) in an anhydrous solvent like tetrahydrofuran (THF). The reaction typically requires a mild base and is carried out at low temperature to achieve high selectivity and yield.

TOTU (CAS: 136849-72-4) is primarily used in the pharmaceutical industry for the synthesis of biologically active molecules. It is also utilized in the polymer industry for the preparation of specialized polymers and in the sensor and semiconductor industries for the development of sensing materials and components.

When handling TOTU (CAS: 136849-72-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its reactivity. Spills should be cleaned up immediately with appropriate absorbent materials and proper disposal methods. Always consult a Safety Data Sheet (SDS) for detailed handling instructions and emergency measures.