Compound Q&A
How is TOTU (CAS: 136849-72-4) typically synthesized?
Answer
TOTU (CAS: 136849-72-4) is synthesized through the alkylation of an appropriate thioester with an organometallic reagent like lithium diisopropylamide (LDA) in an anhydrous solvent like tetrahydrofuran (THF). The reaction typically requires a mild base and is carried out at low temperature to achieve high selectivity and yield.
About
CAS No
136849-72-4
English Name
TOTU
Molecular Formula
C10H17BF4N4O3
Molecular Weight
328.07 g/mol
SMILES
[B-](F)(F)(F)F.CCOC(=O)C(=NOC(=[N+](C)C)N(C)C)C#N
InChIKey
FPQVGDGSRVMNMR-UHFFFAOYSA-N
Last Updated: 2025-10-10 12:21
