6-Bromo-3-nitro-2-pyridinamine(CAS: 84487-04-7)

6-Bromo-3-nitro-2-pyridinamine is a crystalline solid with a molecular weight of approximately 228.04 g/mol. It is slightly soluble in water and has good solubility in common organic solvents such as methanol and acetone. This compound exhibits moderate reactivity, particularly towards nucleophilic substitution and reduction reactions.

6-Bromo-3-nitro-2-pyridinamine is typically synthesized through the bromination of 3-nitro-2-pyridinamine followed by a nitration reaction. Commonly, this involves the use of bromine in the presence of a Lewis acid catalyst and nitric acid for the nitration step, achieving good yields and selectivity under controlled conditions.

6-Bromo-3-nitro-2-pyridinamine is utilized in various industries, including pharmaceuticals for the synthesis of drug intermediates, and in the chemical industry for the production of dyes and other organic compounds. It can also be applied in the development of sensors and as a reagent in analytical chemistry.

Handling 6-Bromo-3-nitro-2-pyridinamine requires appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up carefully, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage recommendations.