S-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl} ethanethioate(CAS: 76931-93-6)

S-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl} ethanethioate is a crystalline compound with a molecular weight of approximately 290.33 g/mol. It has low solubility in water but is soluble in organic solvents. It exhibits reactivity similar to other thiols and can undergo nucleophilic substitution reactions. Its stability is moderate under normal conditions.

S-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl} ethanethioate is synthesized by the condensation reaction of ethanethiol with 2-(2,5-dioxopyrrolidin-1-yl)acetic acid. The reaction is catalyzed by a strong acid such as trifluoroacetic acid, providing a yield of about 85%. The specific conditions and reagents can be optimized for better selectivity.

S-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl} ethanethioate finds applications in pharmaceuticals for its potential as a medicinal intermediate, in polymers for its use in functional materials, and in sensors for its reactivity with various analytes. It is also explored in the semiconductor industry for its electronic properties.

When handling S-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl} ethanethioate, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, immediately contain the spill, clean it up according to the safety data sheet (SDS), and ensure proper disposal. Handling should be done with care to avoid skin contact and inhalation.