(3R)-3-Amino-3-(3-nitrophenyl)propanoic acid(CAS: 787544-61-0)

(3R)-3-Amino-3-(3-nitrophenyl)propanoic acid is a white crystalline solid with a molecular weight of approximately 223.08 g/mol. It has a solubility of about 2.6 mg/mL in water and is slightly soluble in ethanol. Chemically, it is moderately reactive, particularly towards nucleophiles, and can be used in various synthetic reactions.

(3R)-3-Amino-3-(3-nitrophenyl)propanoic acid can be synthesized via a multi-step process involving nitration of an appropriate aromatic compound followed by coupling with an amino acid. Common catalysts include sulfuric acid, and the overall yield is generally around 70-80%. This compound can also be prepared through direct amidation of a nitrobenzene derivative with an amino acid.

(3R)-3-Amino-3-(3-nitrophenyl)propanoic acid is primarily used in pharmaceuticals for the development of novel drug candidates. It also finds applications in the synthesis of certain polymers and as a reagent in chemical sensors for detecting specific compounds. This compound's unique structure makes it valuable in various industries requiring specific chemical functionalities.

When handling (3R)-3-Amino-3-(3-nitrophenyl)propanoic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials, followed by rinsing with water. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.