(R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid

Basic Information

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CAS Number

73025-69-1

Molecular Formula

C9H11NO3

Molecular Weight

181.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

402.3ºC at 760 mmHg

Density

1.329

Flash Point

182.9 °C

SMILES

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C1=CC(=CC=C1C(CC(=O)O)N)O

InChI

InChI=1S/C9H11NO3/c10-8(5-9(12)13)6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m1/s1

InChIKey

JYPHNHPXFNEZBR-MRVPVSSYSA-N

LogP

0.8666999999999994

Topological Polar Surface Area

83.55 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

176

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AC-22039
CS-0179111
CHEBI:180998
R-3-Amino-3-(4-hydroxy-phenyl)-propionic acid
SCHEMBL2765505
AKOS006343478
(R)-beta-tyrosine
(R)-3-Amino-3-(4-hydroxy-phenyl)-propionic acid
(R)-3-Amino-3-(4-hydroxyphenyl)propanoicacid
MFCD04113666
H-Phg(4-OH)-(C#CH2)OH
73025-68-0
73025-69-1
(3R)-3-amino-3-(4-hydroxyphenyl)propanoic acid
(R)-3-Amino-3-(4-hydroxyphenyl)propionic acid
(R)-3-Amino-3-(4-hydroxyphenyl)propanoic acid
(R)-3-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONIC ACID
(R)-3-Amino-3-(4-hydroxyphenyl)-propionic acid
3-Amino-3-(4-hydroxyphenyl)propanoic acid
S-4-NO2-PHA
H-D-b-Phe(4-OH)-OH
H-PHG(4-OH)-(C*CH2)OH

MDL Number

MFCD04113666

Customs Code

2922509090

FAQ

What are the physical and chemical properties of (R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid (CAS: 73025-69-1)?

(R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid is a crystalline solid with a molecular weight of approximately 217.22 g/mol. It is slightly soluble in water and ethanol, with solubility increasing in acidic medium. The compound is reactive towards bases and can undergo condensation reactions. It is used in the pharmaceutical industry for its amino and hydroxy functionalities.

How is (R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid (CAS: 73025-69-1) typically synthesized?

(R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid can be synthesized via asymmetric synthesis using chiral auxiliaries and organocatalysts. Common methods include the use of imine intermediates and kinetic resolution techniques. The yield is typically around 60-70%, and the reaction is conducted under mild conditions to maintain the enantiomeric purity.

What industries use (R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid (CAS: 73025-69-1)?

(R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid is primarily used in the pharmaceutical industry for the development of drugs targeting various diseases, such as Parkinson's disease. It is also used in the synthesis of certain polymers and in the production of sensors and semiconductors due to its unique functional groups.

What precautions should be taken when handling (R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid (CAS: 73025-69-1)?

When handling (R)-3-Amino-3-(4-hydroxy-phenyl)propionic Acid, it is important to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, use appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further instructions. Fume hoods should be used during operations to minimize exposure to the compound.