2'-Deoxy-2'-fluoro-2'-methyluridine(CAS: 863329-66-2)

2'-Deoxy-2'-fluoro-2'-methyluridine is a modified nucleoside with the chemical formula C10H13FN4O5. It features a fluorine and methyl group at the 2' position of the ribose ring, altering its properties compared to natural uridine. This compound is a white solid and exhibits solubility in polar solvents. Its structural modifications make it a key candidate for pharmaceutical and research applications, particularly in nucleic acid studies.

2'-Deoxy-2'-fluoro-2'-methyluridine is primarily used in pharmaceutical research as a nucleoside analog, with potential applications in antiviral and anticancer drug development. It is also employed in molecular biology studies to investigate RNA structure and function, and in biochemical assays to explore nucleic acid interactions. Its unique chemical properties make it valuable for synthetic chemistry and drug design.

2'-Deoxy-2'-fluoro-2'-methyluridine is generally considered safe when handled properly, but it may cause mild irritation upon contact with skin or eyes. Safety data sheets (SDS) recommend using protective gloves, goggles, and ventilation. It is not classified as highly toxic, but standard laboratory safety protocols should be followed to minimize exposure risks.

Store 2'-Deoxy-2'-fluoro-2'-methyluridine in a sealed container at room temperature (15-25°C), away from moisture and light. Maintain low humidity conditions to prevent degradation. For long-term stability, refrigeration (2-8°C) may be necessary. Always keep the container tightly closed and ensure it is stored in a secure, well-ventilated area.