Atovaquone(CAS: 95233-18-4)

Atovaquone (95233-18-4) is an antiparasitic compound primarily used in the treatment of malaria. It belongs to the class of 8-aminoquinolone derivatives and has a chemical formula of C19H20N4O4. Atovaquone is known for its ability to inhibit the electron transport chain in parasites, making it effective against Plasmodium species. It is generally a white to off-white powder with good solubility in organic solvents.

Atovaquone (95233-18-4) is mainly used as an antimalarial drug, often combined with proguanil in medications like Malarone. It is also effective against other parasitic infections such as babesiosis and toxoplasmosis. In addition to its pharmaceutical applications, it is used in research for studying antiparasitic mechanisms and in the development of new therapeutic agents. Its unique mode of action makes it a valuable compound in the fight against drug-resistant parasites.

Atovaquone (95233-18-4) is considered safe when used as directed, but it should be handled with care. It has low toxicity in humans and is generally well-tolerated, though some side effects like nausea and headache may occur. Safety standards for handling atovaquone include following standard laboratory protocols and using appropriate protective equipment. It is important to consult medical or safety guidelines before use, especially in high concentrations or prolonged exposure.

Atovaquone (95233-18-4) should be stored in a cool, dry, and dark place to maintain its stability and potency. It is typically kept in a sealed container at a temperature range of 15–30°C. Avoid exposure to moisture, direct sunlight, and high humidity. Proper storage is essential to ensure the compound remains effective and safe for use in pharmaceutical and research settings.