S-(4-Chlorobenzyl) diethylcarbamothioate(CAS: 28249-77-6)

S-(4-Chlorobenzyl) diethylcarbamothioate (CAS: 28249-77-6) is a crystalline compound with a molecular weight of approximately 246.12 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and methanol. The compound is reactive due to the presence of the carbamothioate group, which can undergo nucleophilic substitution reactions.

S-(4-Chlorobenzyl) diethylcarbamothioate is typically synthesized via the reaction of diethyl carbamothioate with 4-chlorobenzyl chloride. The reaction is usually carried out in the presence of a base such as triethylamine and requires a yield of about 85%. The reaction is selective and proceeds smoothly under the chosen conditions.

S-(4-Chlorobenzyl) diethylcarbamothioate (CAS: 28249-77-6) is used in the pharmaceutical industry for its antifungal properties. It is also utilized in the detection of sulfhydryl groups in biological systems, making it useful in sensor applications. Additionally, it may have potential applications in the semiconductor industry due to its chemical structure.

When handling S-(4-Chlorobenzyl) diethylcarbamothioate (CAS: 28249-77-6), ensure proper personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat is worn. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of the compound. Spills should be handled carefully and cleaned up with appropriate chemicals. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.