(3S)-3-(4-{[4'-(Trifluoromethyl)-3-biphenylyl]methoxy}phenyl)-4-hexynoic acid(CAS: 865231-46-5)

(3S)-3-(4-{[4'-(Trifluoromethyl)-3-biphenylyl]methoxy}phenyl)-4-hexynoic acid (CAS: 865231-46-5) is a crystalline solid with a molecular weight of approximately 506.5 g/mol. It has limited water solubility and is moderately soluble in organic solvents such as dichloromethane and acetonitrile. The compound is highly reactive due to its alkyne and methoxy functionalities. It is not flammable but should be handled in a well-ventilated area or fume hood to prevent inhalation of vapors.

(3S)-3-(4-{[4'-(Trifluoromethyl)-3-biphenylyl]methoxy}phenyl)-4-hexynoic acid (CAS: 865231-46-5) can be synthesized via a multi-step process involving the protection of hydroxyl groups, alkylation, and subsequent deprotection. Commonly, sodium hydride is used as a base, and trifluoromethylated biphenyl is reacted with hexynoic acid derivatives. The exact conditions and reagents may vary depending on the specific synthesis route chosen.

(3S)-3-(4-{[4'-(Trifluoromethyl)-3-biphenylyl]methoxy}phenyl)-4-hexynoic acid (CAS: 865231-46-5) is primarily used in the pharmaceutical industry for its potential as a drug candidate. It may also find applications in polymer chemistry for its functional groups that can be utilized in cross-linking and functionalization reactions. Additionally, it could be used in sensor development due to its reactivity and specific chemical functionalities.

When handling (3S)-3-(4-{[4'-(Trifluoromethyl)-3-biphenylyl]methoxy}phenyl)-4-hexynoic acid (CAS: 865231-46-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation of vapors. Spills should be handled with caution using appropriate absorbent materials, and the substance should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.