(2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b][1,3]oxazole | CAS No. 681492-22-8

(2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b][1,3]oxazole

Basic Information

CAS Number

681492-22-8

Molecular Formula

C25H25F3N4O6

Molecular Weight

534.48 g/mol

AD

Basic Physical Properties

Melting Point

195-196℃

Density

1.45

CC1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F

InChI

InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26,27)28/h2-9,14,20H,10-13,15-16H2,1H3/t24-/m1/s1

InChIKey

XDAOLTSRNUSPPH-XMMPIXPASA-N

LogP

5.55600

Complexity

795

Synonyms & References

English

  • NCGC00348214-01
  • OPC-67683
  • UNII-8OOT6M1PC7
  • Delamanid [USAN]
  • SB14863
  • Delamanid; OPC 67683; OPC67683
  • Q15408413
  • [(2R)-2-methyl-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidyl]phenoxy]methyl]-3H-imidazo[2,1-b]oxazol-6-yl]azinic acid
  • EN300-20602812
  • AC-35849
  • 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy)phenoxy]piperidine
  • AS-56105
  • DB11637
  • NS00072495
  • NSC794689
  • NSC-794689
  • CHEMBL218650
  • CS-5866
  • OPC67683
  • Imidazo(2,1-b)oxazole, 2,3-dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl)phenoxy)methyl)-, (2R)-
  • DELAMANID [MI]
  • DTXSID60218326
  • (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo[2,1-b]oxazole
  • deltyba
  • EX-A2414
  • 8OOT6M1PC7
  • (2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b][1,3]oxazole
  • AKOS025289781
  • OPC 67683
  • OPC-67683; Delamanid
  • DELAMANID [INN]

MDL Number

MFCD18251539

FAQ

What regulatory guidelines apply to (2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b][1,3]oxazole (CAS: 681492-22-8)?

This compound falls under multiple regulatory guidelines such as REACH for European Union manufacturers and exporters, GHS (Globally Harmonized System of Classification and Labelling of Chemicals) for hazard communication, and FDA/EPA regulations for its use in the United States. Ensure compliance with local and international regulations regarding its manufacture, distribution, and disposal.

Are there alternatives to (2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b][1,3]oxazole (CAS: 681492-22-8) in synthesis?

Alternatives to this compound include various other imidazo[2,1-b][1,3]oxazoles with different substituents, which can offer similar or improved properties. Common reagents like trifluoromethoxyphenol and piperidine are widely used in synthetic alternatives.

What is the market or research trend for (2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b][1,3]oxazole (CAS: 681492-22-8)?

The market for this compound is growing due to its potential applications in pharmaceuticals and materials science. Research trends focus on its use in developing novel drugs and functional materials. Market demand is expected to rise as these applications continue to be explored.

How should waste containing (2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b][1,3]oxazole (CAS: 681492-22-8) be handled?

Waste containing this compound should be collected and disposed of in accordance with local and international hazardous waste regulations. Incineration or professional waste disposal services are recommended to ensure proper treatment and environmental protection. Always follow safety and environmental guidelines to prevent contamination.

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