Artemisinic Acid

Basic Information

View in Editor

CAS Number

80286-58-4

Molecular Formula

C15H22O2

Molecular Weight

234.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

129-131 ºC

Boiling Point

373.6℃/760mmHg

Flash Point

273.3°C

Solubility

Methanol; Chloroform

Refractive Index

1.504

SMILES

View in Editor

C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)C(=O)O

InChI

InChI=1S/C15H22O2/c1-9-4-6-12-10(2)5-7-13(14(12)8-9)11(3)15(16)17/h8,10,12-14H,3-7H2,1-2H3,(H,16,17)/t10-,12+,13+,14+/m1/s1

InChIKey

PLQMEXSCSAIXGB-SAXRGWBVSA-N

LogP

3.645800000000002

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

367

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Synonyms & References

English

Artemisinic acid
2-[(1R,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]prop-2-enoic acid
1-Naphthaleneaceticacid, 1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-a-methylene-, (1R,4R,4aS,8aR)-
Artimisinic Acid
Arteannuic acid
Artemisic acid
Qing Hao acid
Qing Hau acid
[ "4", "11(13)-Cadinadien-12-oic acid" ]
(+)-artemisinic acid
53N99527G7
2-((1R,4R,4aS,8aR)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl)prop-2-enoic acid
Artemisinic-acid
PLQMEXSCSAIXGB-SAXRGWBVSA-N
BCP12768
W2206
C20309
222F86B0-6F
s9135
Arteannuic acid,Arteannuinic acid,Artemisic acid,Artemisininic acid,Qing Hao acid,Qing Hau acid

MDL Number

MFCD00238540

FAQ

What is Artemisinic Acid (CAS: 80286-58-4)?

Artemisinic Acid is a sesquiterpene lactone derived from the sweet wormwood plant, *Artemisia annua*. Its chemical formula is C15H26O4, and it is characterized by a complex structure containing a peroxide bridge. It is a white to pale yellow crystalline solid with low solubility in water and moderate solubility in organic solvents. Artemisinic Acid is known for its natural occurrence and is a key precursor in the synthesis of antimalarial drugs like artemisinin.

What are the main uses of Artemisinic Acid (CAS: 80286-58-4)?

Artemisinic Acid is primarily used as a starting material for the production of artemisinin, a potent antimalarial compound. It also finds applications in pharmaceutical research, natural product chemistry, and as a potential source of bioactive compounds. Due to its structural similarity to artemisinin, it is valuable in drug development and therapeutic studies related to malaria treatment.

Is Artemisinic Acid (CAS: 80286-58-4) safe?

Artemisinic Acid is generally considered safe when handled properly. It has low toxicity and is not known to cause significant adverse effects in standard exposure conditions. However, as with any chemical, it should be handled with care using appropriate personal protective equipment (PPE) such as gloves and goggles. Safety data sheets (SDS) should be consulted for detailed handling and disposal guidelines.

How should Artemisinic Acid (CAS: 80286-58-4) be stored?

Artemisinic Acid should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is sensitive to moisture and light, so it should be kept in a sealed container with a desiccant and away from direct sunlight. Proper storage helps maintain its chemical stability and prevents degradation over time.