N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-D-glutamine(CAS: 200623-62-7)

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-D-glutamine has a crystalline form with a molecular weight of approximately 894.5 g/mol. It has low water solubility, making it suitable for organic synthesis. The compound is reactive and can participate in esterification and amidation reactions. It is soluble in organic solvents like DMSO and acetonitrile.

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-D-glutamine is synthesized via a multi-step process involving the coupling of trityl-D-glutamine with 9-(methoxycarbonyl)fluorene. The reaction typically requires a coupling reagent like HATU and a base like DIPEA. The yield is generally around 70-80% with good selectivity.

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-D-glutamine is primarily used in pharmaceuticals and organic synthesis. It serves as a key intermediate in the synthesis of various bioactive compounds. Some applications include drug discovery, polymer synthesis, and as a building block for sensor development and semiconductor fabrication.

Handling N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-D-glutamine requires PPE like gloves, goggles, and a lab coat. Work in a fume hood to avoid inhalation. Spills should be cleaned with solvents, and refer to the SDS for disposal.