Compound Q&A
How is N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-D-glutamine (CAS: 200623-62-7) typically synthesized?
Answer
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N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-D-glutamine is synthesized via a multi-step process involving the coupling of trityl-D-glutamine with 9-(methoxycarbonyl)fluorene. The reaction typically requires a coupling reagent like HATU and a base like DIPEA. The yield is generally around 70-80% with good selectivity.
About
CAS No
200623-62-7
English Name
N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-D-glutamine
Molecular Formula
C39H34N2O5
Molecular Weight
610.71 g/mol
SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)CCC(C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
InChIKey
WDGICUODAOGOMO-PGUFJCEWSA-N
Last Updated: 2025-10-13 15:08
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