[3,5-Bis(trifluoromethyl)phenyl]boronic acid(CAS: 73852-19-4)
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CAS Number
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Basic Information
Molecular Formula
C8H5BF6O2
Molecular Weight
257.93 g/mol
Physical Properties
Melting Point
217-220 °C (lit.)
Boiling Point
128.685°C at 760 mmHg
Density
1.128
Flash Point
64.281℃
Chemical Identifiers
SMILES
B(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)(O)O
InChIKey
BPTABBGLHGBJQR-UHFFFAOYSA-N
Database References
MDL Number
MFCD00051850
Beilstein Registry Number
7379990
FAQ
[3,5-Bis(trifluoromethyl)phenyl]boronic acid (CAS: 73852-19-4) is a boronic acid derivative with a phenyl ring substituted by two trifluoromethyl groups. Its chemical formula is C8H7BF3O2, and it appears as a white crystalline solid. The compound exhibits moderate solubility in organic solvents and is commonly used in organic synthesis due to its reactivity and functional group versatility. Its trifluoromethyl substituents enhance stability and provide unique chemical properties for applications in pharmaceutical and industrial chemistry.
[3,5-Bis(trifluoromethyl)phenyl]boronic acid (CAS: 73852-19-4) is primarily used in pharmaceuticals as a key intermediate in drug development, particularly for molecules requiring fluorinated functionality. It also serves in organic synthesis for Suzuki coupling reactions and other cross-coupling processes. Industrial applications include the production of specialty chemicals, while researchers utilize it in the creation of novel materials and functional compounds. Its unique structure makes it valuable in developing anti-cancer and anti-inflammatory agents.
[3,5-Bis(trifluoromethyl)phenyl]boronic acid (CAS: 73852-19-4) is generally considered safe when handled properly. However, it may pose mild toxicity if ingested or inhaled, so standard safety precautions are recommended. Protective measures include wearing gloves, goggles, and a lab coat to avoid skin and respiratory contact. While not classified as highly hazardous, it should comply with OSHA and REACH regulations for chemical handling. Always follow lab safety guidelines to ensure safe use and disposal.
[3,5-Bis(trifluoromethyl)phenyl]boronic acid (CAS: 73852-19-4) should be stored in a dry, cool place (ideally 2-8°C) away from moisture and light. Keep it in a sealed, airtight container made of glass or HDPE to maintain stability and prevent degradation. Avoid exposure to incompatible substances and store in a well-ventilated area. Proper storage ensures its chemical integrity and extends shelf life for industrial and research applications.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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