Ethyl 2-amino-1-benzothiophene-3-carboxylate(CAS: 7311-95-7)

Ethyl 2-amino-1-benzothiophene-3-carboxylate is a solid at room temperature. It has a molecular weight of approximately 258.34 g/mol and is slightly soluble in water. The compound is reactive towards nucleophiles and can undergo substitution reactions. It also shows good solubility in organic solvents like ethanol and acetone.

Ethyl 2-amino-1-benzothiophene-3-carboxylate is typically synthesized by reacting ethyl 2-bromobenzothiophene-3-carboxylate with ammonium hydroxide in the presence of a base like potassium carbonate. The reaction yields the target compound with good selectivity and a yield of around 70-80%.

Ethyl 2-amino-1-benzothiophene-3-carboxylate is used in the pharmaceutical industry for the synthesis of certain drugs. It is also applied in the chemical industry for the development of sensors and in the electronics industry for the production of semiconductor materials.

When handling Ethyl 2-amino-1-benzothiophene-3-carboxylate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated hood or fume hood. Spills should be cleaned up with appropriate absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.