3,5-Dichloro-2-pyrazinecarboxylic acid(CAS: 312736-49-5)

3,5-Dichloro-2-pyrazinecarboxylic acid (CAS: 312736-49-5) is a crystalline white solid with a molecular weight of approximately 213.04 g/mol. It has a melting point of about 185-186°C and a pKa of around 4.2. The compound is slightly soluble in water but soluble in common organic solvents like methanol and acetonitrile. It shows moderate reactivity towards nucleophiles and can be used as a starting material in various organic synthesis reactions.

3,5-Dichloro-2-pyrazinecarboxylic acid (CAS: 312736-49-5) is typically synthesized via the condensation of 2-chloro-pyrazine with chloroacetyl chloride in the presence of a catalyst like sodium carbonate. The yield is usually around 70-75%, and the reaction is performed under mild conditions to ensure high selectivity and purity.

3,5-Dichloro-2-pyrazinecarboxylic acid (CAS: 312736-49-5) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also utilized in the polymer industry for the production of specialized polymers. Additionally, it has applications in the development of sensors and semiconductors, particularly in the electronics sector.

When handling 3,5-Dichloro-2-pyrazinecarboxylic acid (CAS: 312736-49-5), it is recommended to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a closed container at room temperature and away from direct sunlight. In case of a spill, the area should be ventilated, and appropriate containment measures should be taken to prevent environmental contamination. For further safety information, refer to the Material Safety Data Sheet (MSDS).