Ethyl 5-iodo-2-methylbenzoate(CAS: 612833-45-1)

Ethyl 5-iodo-2-methylbenzoate (CAS: 612833-45-1) has a crystalline form and a molecular weight of approximately 328.05 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound is moderately reactive and can undergo nucleophilic substitution reactions due to the presence of the iodine atom.

Ethyl 5-iodo-2-methylbenzoate (CAS: 612833-45-1) can be synthesized through the Williamson ether synthesis, where 5-iodo-2-methylbenzoic acid is reacted with methyl iodide in the presence of a base like sodium hydroxide. The reaction is typically carried out in an inert solvent like toluene, and the yield is approximately 75-85%.

Ethyl 5-iodo-2-methylbenzoate (CAS: 612833-45-1) is primarily used in the pharmaceutical industry for the synthesis of certain drugs, as a precursor in organic synthesis, and in the chemical industry for the production of various compounds. It is also utilized in the polymer industry as a stabilizer and in the semiconductor industry for photoresist applications.

When handling Ethyl 5-iodo-2-methylbenzoate (CAS: 612833-45-1), wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. Store the compound in a cool, dry place away from direct sunlight. In case of spill, use appropriate spill kits and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.