(2R)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-phenylbutanoic acid(CAS: 135944-09-1)

The compound is a white to off-white crystalline solid with a molecular weight of approximately 432.4 g/mol. It is sparingly soluble in water but soluble in organic solvents. Chemically, it is stable under normal conditions but can be sensitive to strong bases and heat. It can undergo acylation and amide formation reactions.

It is synthesized through multi-step processes involving coupling of fluorenylmethanol with an amino acid via a Fmoc (fluorenylmethoxycarbonyl) strategy. The key steps include protection of the amino group, coupling with the fluorenylmethoxycarbonyl group, and subsequent deprotection to form the final product. The overall yield is around 70%.

This compound is primarily used in pharmaceuticals for the synthesis of certain drugs due to its specific functional groups. It is also used in the polymer industry for the modification of polymer surfaces and in the semiconductor industry for the production of photoresists.

When handling this compound, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be managed using appropriate absorbents, and the compound should be stored in a cool, dry place away from strong acids and bases. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.