Compound Q&A
How is (2R)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-phenylbutanoic acid (CAS: 135944-09-1) typically synthesized?
Answer
![(2R)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-phenylbutanoic acid](https://static.chemtradehub.com/structs/135/135944-09-1-ba72.webp "(2R)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-phenylbutanoic acid")
It is synthesized through multi-step processes involving coupling of fluorenylmethanol with an amino acid via a Fmoc (fluorenylmethoxycarbonyl) strategy. The key steps include protection of the amino group, coupling with the fluorenylmethoxycarbonyl group, and subsequent deprotection to form the final product. The overall yield is around 70%.
About
CAS No
135944-09-1
English Name
(2R)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-phenylbutanoic acid
Molecular Formula
C25H23NO4
Molecular Weight
401.46 g/mol
SMILES
C1=CC=C(C=C1)CCC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
InChIKey
CIHPCIUGLIZADU-HSZRJFAPSA-N
Last Updated: 2025-10-17 07:35
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