Ethyl (diphenoxyphosphoryl)acetate(CAS: 16139-79-0)

Ethyl (diphenoxyphosphoryl)acetate is a colorless to pale yellow liquid with a high specific gravity. Its molecular weight is approximately 322.23 g/mol. This compound is moderately soluble in common organic solvents like ethanol and acetone. It exhibits good reactivity in phosphoryl transfer reactions.

Ethyl (diphenoxyphosphoryl)acetate is synthesized by the reaction of phosphorus pentoxide with ethyl acetate in the presence of diphenoxyphosphoryl chloride. The process involves multistep reactions, with high selectivity and a yield of about 85%. The reaction is typically carried out under anhydrous conditions to prevent side reactions.

Ethyl (diphenoxyphosphoryl)acetate is used in pharmaceuticals for organic synthesis, particularly in the preparation of certain phosphorus-containing compounds. It is also used in the polymer industry for modifying polymer properties and in sensor development for its reactivity with specific chemical species.

Handling Ethyl (diphenoxyphosphoryl)acetate requires the use of personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be stored in a well-ventilated area, away from heat and ignition sources. In case of spill, avoid direct contact and use appropriate PPE. Refer to the Safety Data Sheet (SDS) for detailed emergency procedures.