Compound Q&A

How is Ethyl (diphenoxyphosphoryl)acetate (CAS: 16139-79-0) typically synthesized?

Answer

Ethyl (diphenoxyphosphoryl)acetate
Ethyl (diphenoxyphosphoryl)acetate is synthesized by the reaction of phosphorus pentoxide with ethyl acetate in the presence of diphenoxyphosphoryl chloride. The process involves multistep reactions, with high selectivity and a yield of about 85%. The reaction is typically carried out under anhydrous conditions to prevent side reactions.

About

CAS No 16139-79-0
English Name Ethyl (diphenoxyphosphoryl)acetate
Molecular Formula C16H17O5P
Molecular Weight 320.28 g/mol
SMILES CCOC(=O)CP(=O)(OC1=CC=CC=C1)OC2=CC=CC=C2
InChIKey UQMFCYBSUVRGNU-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55

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