2,4-Dichloro-5-nitropyrimidine(CAS: 49845-33-2)

2,4-Dichloro-5-nitropyrimidine (CAS: 49845-33-2) is a crystalline solid with a molecular weight of approximately 231.04 g/mol. It has a high solubility in organic solvents like methanol and is only slightly soluble in water. This compound is highly reactive and can undergo substitution reactions and nitration. It decomposes above 200°C and should be stored in a cool, dry place away from moisture and heat sources.

2,4-Dichloro-5-nitropyrimidine (CAS: 49845-33-2) is usually synthesized by the nitration of 2,4-dichloropyrimidine. The reaction is typically carried out using concentrated nitric acid under carefully controlled conditions. The process requires strict temperature and concentration control to achieve the desired yield and selectivity. The reaction mixture is then purified by recrystallization to obtain the pure compound.

2,4-Dichloro-5-nitropyrimidine (CAS: 49845-33-2) is used in various industries, particularly in pharmaceuticals for the synthesis of certain drugs. It is also used in the production of specialty chemicals, as a precursor in the polymer industry, and in the development of sensors and semiconductors due to its unique chemical properties.

When handling 2,4-Dichloro-5-nitropyrimidine (CAS: 49845-33-2), it is crucial to wear proper personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled carefully using appropriate absorbents, and the material safety data sheet (MSDS) or safety data sheet (SDS) should be consulted for detailed handling instructions. Storage should be in a cool, dry place away from heat and ignition sources.