2-Bromo-5-nitro-3-(trifluoromethyl)pyridine(CAS: 956104-42-0)

2-Bromo-5-nitro-3-(trifluoromethyl)pyridine (CAS: 956104-42-0) is a crystalline solid with a molecular weight of approximately 318.03 g/mol. It is slightly soluble in water but more soluble in organic solvents like dichloromethane and acetonitrile. This compound is known for its high reactivity, particularly towards nucleophiles and reducing agents.

2-Bromo-5-nitro-3-(trifluoromethyl)pyridine is typically synthesized through bromination of 5-nitro-3-(trifluoromethyl)pyridine followed by the introduction of a bromine atom. Commonly used reagents include N-bromosuccinimide (NBS) in the presence of a radical initiator like AIBN. The synthesis involves multiple steps and requires careful control of reaction conditions to achieve high yields.

2-Bromo-5-nitro-3-(trifluoromethyl)pyridine (CAS: 956104-42-0) is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It also finds applications in the field of organic chemistry as a building block for complex molecule synthesis and in the development of new materials for electronic devices.

When handling 2-Bromo-5-nitro-3-(trifluoromethyl)pyridine (CAS: 956104-42-0), it is crucial to use proper personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight and oxidizing agents. It should be handled in a well-ventilated area or a fume hood due to its potential to release toxic fumes. In case of a spill, immediately clean up with appropriate absorbents and consult the Safety Data Sheet (SDS) for detailed instructions.