(5-Methyl-1-benzothiophen-2-yl)boronic acid(CAS: 136099-65-5)

(5-Methyl-1-benzothiophen-2-yl)boronic acid is a solid with a crystalline form. It has a molecular weight of approximately 283.3 g/mol and is slightly soluble in water. It is reactive and readily forms coordination complexes with various metals. This compound is often used in organic synthesis due to its reactivity and specific functional groups.

(5-Methyl-1-benzothiophen-2-yl)boronic acid is typically synthesized via a Suzuki coupling reaction, where a boronic acid reacts with a bromo or iodo benzothiophene derivative in the presence of a palladium catalyst and a base. This method provides high selectivity and yield, making it a common approach in synthetic chemistry.

(5-Methyl-1-benzothiophen-2-yl)boronic acid is used in the pharmaceutical industry for the synthesis of先导化合物和药物中间体，以及在聚合物和半导体领域中作为功能材料。此外，它还被用于传感器和电子材料的制备中。

When handling (5-Methyl-1-benzothiophen-2-yl)boronic acid, it is important to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.