(1S,3R)-3-Aminocyclopentanecarboxylic acid(CAS: 71830-07-4)

(1S,3R)-3-Aminocyclopentanecarboxylic acid is a white crystalline solid with a molecular weight of approximately 137.16 g/mol. It is slightly soluble in water and has good solubility in organic solvents. The compound is known for its reactivity in amide and ester formation reactions. It has a melting point of about 180°C and exhibits basic properties due to the amine group.

(1S,3R)-3-Aminocyclopentanecarboxylic acid can be synthesized through the reduction of (1S,3R)-3-cyclopentanecarboxylic acid with sodium borohydride, followed by the addition of ammonia. The reaction yields the desired acid in good yield with high stereoselectivity. This method involves mild conditions and is commonly used in laboratory settings for preparing this compound.

(1S,3R)-3-Aminocyclopentanecarboxylic acid is mainly used in the pharmaceutical industry for the synthesis of various drug candidates. It also finds applications in the polymer industry as a monomer for preparing functional polymers. Additionally, it is used in sensor development and as a reagent in chemical research for its reactivity in amide and ester formation reactions.

When handling (1S,3R)-3-Aminocyclopentanecarboxylic acid, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to avoid inhalation of fumes. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.