1-(3-Nitrophenyl)methanamine hydrochloride (1:1)(CAS: 26177-43-5)

1-(3-Nitrophenyl)methanamine hydrochloride (CAS: 26177-43-5) is a crystalline compound with a molecular weight of approximately 223.07 g/mol. It has a solubility of about 20 g/L in water at 25°C. The compound is moderately reactive, particularly towards basic conditions, and can undergo hydrolysis. It has a pKa of around 2.5, indicating a strong acidic nature due to the presence of the hydrochloride ion.

1-(3-Nitrophenyl)methanamine hydrochloride (CAS: 26177-43-5) is typically synthesized by reacting 3-nitrophenylamine with hydrochloric acid. The reaction proceeds via protonation of 3-nitrophenylamine followed by crystallization. Commonly, the reaction mixture is heated to promote the reaction, and the product is then isolated via filtration and recrystallization from aqueous solutions.

1-(3-Nitrophenyl)methanamine hydrochloride (CAS: 26177-43-5) finds applications in the pharmaceutical industry, where it serves as an intermediate in the synthesis of certain drug compounds. It is also used in the production of sensors and semiconductors due to its unique chemical properties. Additionally, it can be utilized in polymer chemistry for specific functionalization purposes.

Proper handling of 1-(3-Nitrophenyl)methanamine hydrochloride (CAS: 26177-43-5) requires the use of personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure to fumes. In case of a spill, it should be cleaned up carefully according to the Material Safety Data Sheet (MSDS/SDS) guidelines. Spills should be neutralized with a basic solution before disposal. Storage should be in a cool, dry place, away from sources of heat and ignition.