3-(3-Chlorophenyl)acrylic acid(CAS: 1866-38-2)

3-(3-Chlorophenyl)acrylic acid (CAS: 1866-38-2) is a crystalline solid with a molecular weight of approximately 183.65 g/mol. It has a pKa of around 3.5 and is slightly soluble in water. The compound is reactive and can undergo polymerization and condensation reactions under certain conditions. It is typically used in organic synthesis and as a precursor in various chemical processes.

3-(3-Chlorophenyl)acrylic acid is commonly synthesized via the chlorination of 3-phenylacrylic acid followed by acetylation. This process involves the use of chlorine gas and acetyl chloride as reagents. The yield can be up to 85%, and the reaction is typically catalyzed by strong acids like sulfuric acid. High selectivity and purity can be achieved using appropriate techniques.

3-(3-Chlorophenyl)acrylic acid (CAS: 1866-38-2) finds applications in pharmaceuticals, where it serves as an intermediate in the synthesis of drug molecules. It is also used in the production of polymers, sensors, and semiconductors due to its functional groups that enhance material properties. Its reactivity and versatility make it a valuable compound in these industries.

When handling 3-(3-Chlorophenyl)acrylic acid (CAS: 1866-38-2), it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a fume hood to prevent exposure to vapors. Store the compound in a sealed container away from heat and incompatible materials. In case of spills, neutralize with a base and clean up with absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.